Amyloid-beta
Domain : Pathophysiology
Category : My daily life
Simplified definition
A small protein normally present in the brain, but which is eliminated by the body before it becomes toxic.
Source: Houria Aiouaz, for Alzheimer Foundation
Referenced definition
“Amyloid beta peptide[s] […] derive [sic] […] from the precursor protein, amyloid beta precursor protein (APP).”
Source: Rukmangadachar LA, Bollu PC. Amyloid Beta Peptide. Treasure Island (FL): StatPearls Publishing, 2022.
Context
In AD, amyloid-beta is not properly eliminated by the body and accumulates in the brain until it forms amyloid plaques.
Source: Olivier Hanon, member of the Alzheimer Foundation operational committee (ComOP)
Note
- A form of amyloid-beta peptide, called Aβ42, has aggregating properties that explain the progressive formation of amyloid plaques.
Abbreviation(s)
AβSpelling variation(s)
Amyloid-β / Amyloid betaGO FURTHER
