Biomarker
Domain : Diagnosis
Category : My daily life
Simplified definition
Biomarkers are measurable evidence, found in the body thanks to medical examination, of a disease or certain conditions.
Source: Houria Aiouaz, for Alzheimer Foundation
Referenced definition
“A characteristic that is objectively measured and evaluated as an indicator of normal biologic processes, pathogenic processes, or pharmacologic responses to a therapeutic intervention.”
Source: Openmd. Biomarker. [Internet]. [cited on Sept 7, 2022].
Context
“No single biomarker can by itself accurately diagnose AD. A combination of biomarkers assessed through imaging and cerebrospinal fluid (CSF) yields better diagnostic accuracy.”
Source: Khoury R, Ghossoub E. Diagnostic biomarkers of Alzheimer’s disease: A state-of-the-art review. Biomarkers in Neuropsychiatry. 2019;1.
Note
- Amyloid-beta and Tau are biomarkers for Alzheimer’s disease that can be found in cerebrospinal fluid during diagnosis.