Hippocampus
Domain : Pathophysiology
Category : Learn more
Simplified definition
Small area in the temporal lobes of the brain which is responsible for memory and learning.
Source: Houria Aiouaz, for Alzheimer Foundation
Referenced definition
“Region of the brain that is associated primarily with memory. […] The hippocampus, which is located in the inner (medial) region of the temporal lobe, forms part of the limbic system, which is particularly important in regulating emotional responses.”
Source: Britannica. Hippocampus. [Internet]. 2023 [cited on May 8, 2023].
Context
“The hippocampus is one of the earliest affected brain regions in Alzheimer’s disease (AD) and its dysfunction is believed to underlie the core feature of the disease-memory impairment.”
Source: Maruszak A, Thuret S. Why looking at the whole hippocampus is not enough—a critical role for anteroposterior axis, subfield and activation analyses to enhance predictive value of hippocampal changes for Alzheimer’s disease diagnosis. Frontiers in Cellular Neuroscience. 2014;8:95.
Note
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